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CHEM 3341: Laboratory for Organic Chemistry II

This lab course is for biochemistry and non-chemistry majors. Chem 3341 is a continuation of Chem 3321, Organic Chemistry I Lab. The laboratory techniques learned in 3321 are used to carry out reactions in aromatic substitution, organometallic chemistry, oxidation and reduction chemistry, esterifications, aldol condensations, and azo dye chemistry. A significant portion of the semester is devoted to determining the structure of unknown organic compounds, both theoretically in the spectroscopy section and practically in the separation and identification of an unknown compound, as well as verifying the identification of compounds synthesized in lab.

TA office hours and emails are posted here.

LabDayTimeLocationTA
201M1:00 PMEKLC M1B20Will (Duk) Yi
211M5:00 PMEKLC M1B20Tianyi Yang
221T9:00 AMEKLC M1B20Ryo Tamura
222T9:00 AMEKLC M1B25Zhenyi Hu
231T1:00 PMEKLC M1B20Jessica Burl
232T1:00 PMEKLC M1B25Mitch Magrini
241W1:00 PMEKLC M1B20Yaohao Li
242W1:00 PMEKLC M1B25Yiming Hu
251W5:00 PMEKLC M1B20Yaohao Li
252W5:00 PMEKLC M1B25Dayan Wei
261R9:00 AMEKLC M1B20Alyssa Scarbrough
262R9:00 AMEKLC M1B25Aaron Crossman
271R1:00 PMEKLC M1B20Mitch Magrini
272R1:00 PMEKLC M1B25Aaron Crossman
281R5:00 PMEKLC M1B20Mitch Magrini
282R5:00 PMEKLC M1B25Yiming Hu
291F1:00 PMEKLC M1B20Aaron Crossman

Schedule for Spring 2017

Dates Experiment Bring Quiz Notes
Jan 16-20 Labs will not meet
Jan 23-27 Lab check-in & NMR Review (nothing) No If you don't remember NMR from OChem 1, read up on it ahead of time. These sources are helpful:
Chapters 18 & 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet and the Spectroscopy Homework are not due as part of this lab, but they may be helpful.
Jan 30 – Feb 3 Exp. 14: Epoxidation of Cholesterol Prelab Yes (SQ Answers) This is the first experiment this term that has a full lab report associated with it. Be sure to print a copy of the lab report rubric and attach it to your lab report when you turn it in at the next lab session. The Handbook contains a chapter on writing lab reports.
Lab Safety (for review!)
Feb 6-10 Exp. 15: Diels-Alder Reaction Prelab Yes (SQ Answers)
Feb 13-17 Exp. 16: Electrophilic Aromatic Substitution Prelab Yes (SQ Answers)
Feb 20-24 Exp. 17: Microscale Column Chromatography Prelab Yes (SQ Answers) See the section on how to run a flash column in the Column Chromatography Section.
Feb 27 – Mar 3 Exp. 18: Nucleophilic Aromatic Substitution Prelab Yes (SQ Answers) You will need the Handbook supplement on Microwave-Assisted Chemistry
Mar 6-10 Exp. 19: Identification of Unknowns, day 1 Prelab Yes (SQ Answers) Identification of Unknowns rubric
A visual guide to this lab
NMR spectra for all compounds
Mar 13-17 Exp. 19: Identification of Unknowns, day 2 (nothing) No The ID of Unknowns paper is due three lab periods from now.
Mar 20-24 Exp. 20: Reduction of Ketones Prelab Yes (SQ Answers)
Mar 27-31 Labs will not meet
Apr 3-7 Exp. 21: Grignard Dyes Prelab Yes (SQ Answers) You will need the Handbook supplement on UV-Visible and Fluorescence Spectroscopy.
Apr 10-14 Exp. 22: Liquid Crystals Prelab, ID of Unknowns paper Yes (SQ Answers)
Apr 17-21 Exp. 23: Fischer Esterification Prelab Yes (SQ Answers) NMR spectra of all 5 esters. Note that these are for the methyl esters, not the ethyl esters, so you will have to keep this in mind when comparing your own spectra.
Apr 24-28 Exp. 24: Aldol Condensation Prelab Yes (SQ Answers) You will need the Handbook supplements on Green Chemistry and UV-Visible and Fluorescence Spectroscopy.
May 1-5 Lab Check-out & Final Quiz Buff Onecard Yes For the final quiz, you should review the study questions and prelab quizzes.