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CHEM 3341: Laboratory for Organic Chemistry II

This lab course is for biochemistry and non-chemistry majors. Chem 3341 is a continuation of Chem 3321, Organic Chemistry I Lab. The laboratory techniques learned in 3321 are used to carry out reactions in aromatic substitution, organometallic chemistry, oxidation and reduction chemistry, esterifications, aldol condensations, and azo dye chemistry. A significant portion of the semester is devoted to determining the structure of unknown organic compounds, both theoretically in the spectroscopy section and practically in the separation and identification of an unknown compound, as well as verifying the identification of compounds synthesized in lab.

TA office hours and emails are posted here.

LabDayTimeLocationTA

Schedule for Summer 2017

Day Experiment Bring Quiz Notes
Tue Jul 11 Lab check-in & NMR Review (nothing) No If you don't remember NMR from OChem 1, read up on it ahead of time. These sources are helpful:
Chapters 18 & 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet, the Spectroscopy Homework, and the Practical NMR lab are not due as part of this lab, but they may be helpful.
Wed Jul 12 Exp. 14: Microscale Column Chromatography Prelab Yes (SQ Answers) See the section on how to run a flash column in the Column Chromatography Section.
This is the first experiment this term that has a full lab report associated with it. Be sure to print a copy of the lab report rubric and attach it to your lab report when you turn it in at the next lab session. The Handbook contains a chapter on writing lab reports.
Lab Safety (for review!)
Thu Jul 13 Exp. 15: Identification of Unknowns, day 1 Prelab Yes (SQ Answers) Identification of Unknowns rubric
A visual guide to this lab
NMR spectra for all compounds
Tue Jul 18 Exp. 15: Identification of Unknowns, day 2 (nothing) No The ID of Unknowns paper is due three lab periods from now.
Wed Jul 19 Exp. 16: Epoxidation of Cholesterol Prelab Yes (SQ Answers)
Thu Jul 20 Exp. 17: Grignard Dyes Prelab Yes (SQ Answers) You will need the Handbook supplement on UV-Visible and Fluorescence Spectroscopy.
Tue Jul 25 Exp. 18: Reduction of Ketones Prelab, ID of Unknowns paper Yes (SQ Answers)
Wed Jul 26 Exp. 19: Wittig Reaction Prelab Yes (SQ Answers) You will need the Handbook supplement on Microwave-Assisted Chemistry
Thu Jul 27 Exp. 20: Liquid Crystals Prelab Yes (SQ Answers)
Tue Aug 1 Exp. 21: Fischer Esterification Prelab Yes (SQ Answers) NMR spectra of all 5 esters. Note that these are for the methyl esters, not the ethyl esters, so you will have to keep this in mind when comparing your own spectra.
Wed Aug 2 Exp. 22: Aldol Condensation Prelab Yes (SQ Answers) You will need the Handbook supplements on Green Chemistry and UV-Visible and Fluorescence Spectroscopy.
Thu Aug 3 Exp. 23: Diels-Alder Reaction Prelab Yes (SQ Answers)
Tue Aug 8 Exp. 24: Electrophilic Aromatic Substitution Prelab Yes (SQ Answers)
Wed Aug 9 Lab Check-out & Final Quiz Buff Onecard Yes For the final quiz, you should review the study questions and prelab quizzes.
Thu Aug 10 Labs will not meet