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CHEM 3321: Laboratory for Organic Chemistry I

This lab course is for biochemistry and non-chemistry majors. A large part of Chem 3321 is spent learning techniques in organic chemistry, including TLC, distillation, extraction, crystallization, and IR spectroscopy. Once these techniques are mastered, they are employed in the final four labs of the semester. Two laboratory periods are devoted to working with molecular models sets to study nomenclature, conformational analysis, and stereochemistry.

TA office hours and emails are posted here.

LabDayTimeLocationTA
101M1:00 PM-3:50 PMEKLC M1B20Sara Robertson
102M1:00 PM-3:50 PMEKLC M1B25Josh Kamps
111M5:00 PM-7:50 PMEKLC M1B20Dylan Mori
112M5:00 PM-7:50 PMEKLC M1B25Josh Kamps
113M5:00 PM-7:50 PMEKLC M1B35Tianyi Yang
121T9:00 AM-11:50 AMEKLC M1B20Will Yi
122T9:00 AM-11:50 AMEKLC M1B25Zepeng Lei
131T1:00 PM-3:50 PMEKLC M1B20Patrick Li
132T1:00 PM-3:50 PMEKLC M1B25Chance Brandt
141W1:00 PM-3:50 PMEKLC M1B20Sara Robertson
142W1:00 PM-3:50 PMEKLC M1B25Zhenhao Chen
151W5:00 PM-7:50 PMEKLC M1B20Patrick Nordeen
152W5:00 PM-7:50 PMEKLC M1B25Zhenyi Hu
153W5:00 PM-7:50 PMEKLC M1B35Matthew Farmer
161R9:00 AM-11:50 AMEKLC M1B20Chance Brandt
162R9:00 AM-11:50 AMEKLC M1B25Aaron Crossman
171R1:00 PM-3:50 PMEKLC M1B20Patrick Li
172R1:00 PM-3:50 PMEKLC M1B25Aaron Crossman
181R5:00 PM-7:50 PMEKLC M1B20Aaron Crossman
182R5:00 PM-7:50 PMEKLC M1B25Josh Kamps
183R5:00 PM-7:50 PMEKLC M1B35Patrick Nordeen
191F1:00 PM-3:50 PMEKLC M1B20Zepeng Lei
192F1:00 PM-3:50 PMEKLC M1B25Zhenhao Chen
193F1:00 PM-3:50 PMEKLC M1B35Matthew Farmer

Experiment Schedule

Dates Experiment Bring Quiz Notes
Mon Aug 28 - Fri Sep 1 Lab Check-in & Exp. 1: Lab Safety, ChemDraw & Excel Experiment Manual; laptop if you have one Yes Be sure to read the safety chapter in the handbook before lab. In case you haven't purchased the lab books yet, Experiment 1 and the safety chapter are available as PDFs. This Lab Safety Movie may also help.
You can also save time by downloading and installing ChemDraw ahead of time.
Tue Sep 5 - Mon Sep 11 Exp. 2: IR Spectroscopy & Modeling Conformations (nothing) No From this point on, Monday sections will do each experiment after all the other sections.
IR Tutorial
You can check out a model set if you don't have one.
Tue Sep 12 - Mon Sep 18 Exp. 3: NMR Spectroscopy (nothing) No Chapters 18 & 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet (in the experiment manual) is due before you leave today. The Spectroscopy Homework is due later. Download this file and print the pages you are assigned.
Tue Sep 19 - Mon Sep 25 Exp. 4: Practical NMR Completed Spectroscopy Homework, Laptop if you have one Yes You will need to download and install MestreNova. NMR data files can be downloaded for this lab.
Tue Sep 26 - Mon Oct 2 Exp. 5: Thin Layer Chromatography and Melting Point Prelab Yes (SQ Answers) This is the first experiment this term that has a full lab report associated with it. Be sure to print a copy of the lab report rubric and attach it to your lab report when you turn it in at the next lab session.
TLC procedure and more
Melting points
Melting point movie (10:45 into the Crystallization movie)
Tue Oct 3 - Mon Oct 9 Exp. 6: Extraction Prelab Yes (SQ Answers) Extraction procedure
Extraction movie
Remember to save the product from this lab for the next lab.
Tue Oct 10 - Mon Oct 16 Exp. 7: Recrystallization Prelab Yes (SQ Answers) Recrystallization movie
Recrystallization procedure
Tue Oct 17 - Mon Oct 23 Exp. 8: Distillation Prelab Yes (SQ Answers) Distillation procedure GC Movie
Tue Oct 24 - Mon Oct 30 Exp. 9: Isolation of Limonene Prelab Yes (SQ Answers) You will need the Handbook supplements on Green Chemistry and Optical Activity and Polarimetry.
Tue Oct 31 - Mon Nov 6 Exp. 10: Modelling Chirality & Cycloalkanes No You can check out a model set if you don't have one.
Tue Nov 7 - Mon Nov 13 Exp. 11: Stereochemistry of Alkene Additions Prelab and worksheet No Instead of a prelab quiz, fill in the worksheet included with the lab.
You will need the Handbook supplement on Green Chemistry.
Tue Nov 14 - Fri Nov 17 Exp. 12: Regiochemistry of Eliminations Prelab Yes (SQ Answers) You can download the NMR spectrum for 3-methylcyclohexene.
Mon Nov 20 - Fri Nov 24 No labs
Mon Nov 27 Monday labs complete Exp. 12: Regiochemistry of Eliminations Prelab Yes (SQ Answers) You can download the NMR spectrum for 3-methylcyclohexene.
Tue Nov 28 - Mon Dec 4 Exp. 13: Oxidation of Alcohols Prelab Yes (SQ Answers)
Tue Dec 5 - Mon Dec 11 Lab Check-out & Final Quiz Buff Onecard Yes For the final quiz, you should review the study questions, worksheets and prelab quizzes.