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CHEM 3321: Laboratory for Organic Chemistry I

This lab course is for biochemistry and non-chemistry majors. A large part of Chem 3321 is spent learning techniques in organic chemistry, including TLC, distillation, extraction, crystallization, and IR spectroscopy. Once these techniques are mastered, they are employed in the final four labs of the semester. Two laboratory periods are devoted to working with molecular models sets to study nomenclature, conformational analysis, and stereochemistry.

TA office hours and emails are posted here.

101M1:00 PMEKLC M1B25Charlie Martin
111M5:00 PMEKLC M1B25Josh Kamps
112M5:00 PMEKLC M1B35Yaohao Li
132T1:00 PMEKLC M1B35Charlie Martin
152W5:00 PMEKLC M1B35Josh Kamps
172R1:00 PMEKLC M1B35Eric Miller
182R5:00 PMEKLC M1B35Eric Miller
183R5:00 PMEKLC M1B65Will (Duk) Yi
192F1:00 PMEKLC M1B35Michael Ortiz
193F1:00 PMEKLC M1B65Will (Duk) Yi

Schedule for Spring 2017

Dates Experiment Bring Quiz Notes
Jan 16-20 Labs will not meet
Jan 23-27 Lab Check-in & Exp. 1: Lab Safety, ChemDraw & Excel Experiment Manual; laptop if you have one Yes Be sure to read the safety chapter in the handbook before lab. In case you haven't purchased the lab books yet, Experiment 1 and the safety chapter are available as PDFs. This Lab Safety Movie may also help.
You can also save time by downloading and installing ChemDraw ahead of time.
Jan 30 – Feb 3 Exp. 2: Thin Layer Chromatography and Melting Point Prelab Yes (SQ Answers) This is the first experiment this term that has a full lab report associated with it. Be sure to print a copy of the lab report rubric and attach it to your lab report when you turn it in at the next lab session.
TLC procedure and more
Melting points
Melting point movie (10:45 into the Crystallization movie)
Feb 6-10 Exp. 3: IR Spectroscopy & Modeling Conformations (nothing) No IR Tutorial
You can check out a model set if you don't have one.
Feb 13-17 Exp. 4: Extraction Prelab Yes (SQ Answers) Extraction procedure
Extraction movie
Remember to save the product from this lab for the next lab.
Feb 20-24 Exp. 5: Recrystallization Prelab Yes (SQ Answers) Recrystallization movie
Recrystallization procedure
Feb 27 – Mar 3 Exp. 6: NMR Spectroscopy (nothing) No Chapters 18 & 20 in the Lab Handbook and Chapter 13 in Loudon; Spectroscopy Tutorial and NMR Theory Tutorial on this web site.
The in-class Spectroscopy Worksheet (in the experiment manual) is due before you leave today. The Spectroscopy Homework is due in one week. Download this file and print the pages you are assigned.
Mar 6-10 Exp. 7: Practical NMR Completed Spectroscopy Homework and laptop if you have one Yes You will need to download and install MestreNova. NMR data files can be downloaded for this lab.
Mar 13-17 Exp. 8: Isolation of Limonene Prelab Yes (SQ Answers) You will need the Handbook supplements on Green Chemistry and Optical Activity and Polarimetry.
Mar 20-24 Exp. 9: Distillation Prelab Yes (SQ Answers) Distillation procedure GC Movie
Mar 27-31 Labs will not meet
Apr 3-7 Exp. 10: Stereochemistry of Alkene Additions Prelab and worksheet No Instead of a prelab quiz, fill in the worksheet included with the lab.
You will need the Handbook supplement on Green Chemistry.
Apr 10-14 Exp. 11: Modelling Chirality & Cycloalkanes No You can check out a model set if you don't have one.
Apr 17-21 Exp. 12: Regiochemistry of Eliminations Prelab Yes (SQ Answers) You can download the NMR spectrum for 3-methylcyclohexene.
Apr 24-28 Exp. 13: Oxidation of Alcohols Prelab Yes (SQ Answers)
May 1-5 Lab Check-out & Final Quiz Buff Onecard Yes For the final quiz, you should review the study questions, worksheets and prelab quizzes.